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Emergency Contact 24h

0900 712 712

(3.23 CHF / min. from the Swiss landline, possibly additionally 8 Rp. / min. by network operator)

 
 

0900 712 713

(3.12 CHF / min. for calls from prepaid cell phones, possibly additionally 8 Rp. / min. by network operator)


Important Numbers

  • 144   Ambulance
  • 145   Tox Center (Poisoning)
  • 117   Police
  • 118   Fire Department

Kontakt Box

UKBB

University Children’s Hospital Basel
Spitalstrasse 33
4056 Basel
Switzerland

T +41 61 704 12 12
F +41 61 704 12 13

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For making an appointment or the postponement of an appointment, please contact polyclinic head office +41 61 704 12 20

 
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Fetal and Neonatal Stress Research

The goal of our research group is to better understand the transition from intra- to extra-uterine life and to examine therapeutic strategies against transition failure. The process of vaginal birth prepares the baby for the extra-uterine environment and, in comparison to babies delivered by elective cesarean section, confers respiratory, cardiovascular and immunological advantages to the newborn.

We investigate the role of stress hormones during birth, including vasopressin/copeptin, the causes and consequences of their release with a particular focus on breathing, weight changes and pain experience in the newborn. In the case of birth complications or premature delivery, e.g. a lack of oxygen (hypoxia-ischemia) can damage the brain owing to long-lasting neurodevelopmental disabilities. Total body hypothermia commenced shortly after birth is an effective therapy to alleviate neuronal damage after perinatal hypoxia-ischemia but the underlying molecular mechanisms of cold protection are poorly understood. Here we concentrate on the two cold-inducible proteins RBM3 and CIRP, which are involved in neuroplasticity and inflammation.

A second strategy for neuroprotection is the administration of erythropoietin. In an international multicenter randomized trial, enrolling preterm neonates with intraventricular hemorrhage or hemorrhagic parenchymal infarction, we test the effect of high-dose erythropoietin on neurodevelopmental outcome (www.eporepair.ch). Our studies are performed in close collaboration with other research groups of the UKBB, with the Department of Obstetrics and Gynecology (Prof. Lapaire) and the Department of Biomedicine (Prof. Guzman) of the University Hospital Basel, the Biozentrum (Prof. Kapfhammer) of the University of Basel, and the Universities of Zurich (PD Dr. Burkhardt) and Oxford (Prof. Slater).

Only available in German

 

Group members

  • Severin Kasser, MD
  • Katrina Evers, MD
  • Xinzhou Zhu, PhD
  • Jingyi Yan, PhD Student
  • Hanna Rickenbacher, MD Student
  • Noemi Klarer, MD Student
  • Claudia Knöpfli, MSc ETH
  • Andrea Zelmer, Dipl. Ing. FH
 

Emergencies

0900 712 712

(3.23 CHF/min. CH-landline, possibly additionally 8 Rp. / min. by network operator)

0900 712 713

(3.12 CHF/min. prepaid cell phones, possibly additionally 8 Rp. / min. by network operator)

Site Map

Contact

University Children’s Hospital Basel
Spitalstrasse 33
4056 Basel / Switzerland

T +41 61 704 12 12
F +41 61 704 12 13

 

Emergency

Contact

University Children’s Hospital Basel
Spitalstrasse 33
4056 Basel / Switzerland

T +41 61 704 12 12
F +41 61 704 12 13

© UKBB, 2018