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Our activities focus on the competent supervision and implementation of mono- and multicentre national and international clinical trials in collaboration with a local project manager at UKBB. We have expertise in the field of academic and industry-sponsored studies and are available to every specialist discipline at UKBB.
We are currently supervising the following studies / projects:
No ongoing studies at present.
Principle Investigator
Prof Dr med Julia Bielicki
Total planned patients
–
Design
Data science implementation hybrid
Pediatric Personalised Research Network Switzerland (SwissPedHealth) - a Joint Pediatric National Data Stream
Principle Investigator
PD Dr Julia Bielicki
Total planned patients
–
Design
national, multicentre
SwissPedHealth Personalised Pediatric Primay care PREPP
Principle Investigator
Prof Jan Bonhoeffer, MD
Total planned patients
–
Design
national, multicentre
SwissPandEmic&AmR Health Economy Awareness Detect
Subproject 2: UTI Risk Prediction Model
Principle Investigator
Prof Dr med Julia Bielicki
Total planned patients
–
Design
national, multicentre
SARS-CoV2 variants Evaluation in pRegnancy and paeDIatrics cohorts - An evaluation of school-based mass PCR testing in Baselland
Principle Investigator
Prof Dr med Julia Bielicki
Total planned patients
–
Design
population-based evaluation
No ongoing studies at present.
Active one health surveillance in LMICs to monitor and predict Antimicrobial Resistance Using Metagenomics
Principle Investigator CH
Prof Dr med Julia Bielicki
Total planned patients
> 1000
Design
International, multicentre
Routine antibiotic prescription and resistance monitoring in primary care physicians: A nationwide pragmatic randomised controlled trial
Principle Investigator
PD Dr Julia Bielicki
Total planned patients
–
Design
population-based
A randomised controlled non-inferiority trial of placebo versus macrolide antibiotics for Mycoplasma pneumoniae infection in children with community-acquired pneumonia
Principle Investigator
PD Dr Julia Bielicki
Total planned patients
380
Design
National, multicentre
Optimised kangaroo care to support breastfeeding and healthy microbiome acquisition in very preterm infants (MINI-KAB) -a substudy of the multicentre, parallel cluster randomised NeoDeco study
Principle Investigator
Dr med Kerstin Jost
Total planned patients
>5000
Design
international, multicentre
Optimising kangaroo care to reduce neonatal severe infection/sepsis and resistant bacterial colonisation among high-risk infants in neonatal intensive care: a pragmatic, multicentre, parallel cluster randomised hybrid implementation-effectiveness trial
Principle Investigator
Dr med Kerstin Jost
Total planned patients
>5000
Design
International, multicentre
Restricted versus liberal fluid intake for prevention of bronchopulmonary dysplasia - RELIEF trial
Principle Investigator
Prof Dr med Sven Schulzke
Total planned patients
700
Design
National, multicentre
Oral propanolol for the prevention of high-grade retinopathy of prematurity
Principle Investigator
Prof Dr med Sven Schulzke
Total planned patients
–
Design
National, multicentre
Capillary versus venous blood test: Validation study for the optimisation of clinical laboratory tests in pediatrics
Principle Investigator
Dr Alexandra Goischke
Total planned patients
100
Design
national, monocentre
A 6-month multicentre, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety and PK/PD of an age-and body weight-adjusted oral finerenone regimen, in
addition to an ACEI or ARB, for the treatment of children, 6 months to <18 years of age, with chronic kidney disease and proteinuria
Principle Investigator
Dr Alexandra Goischke
Total planned patients
2
Design
International, multicentre
An 18-month, open-label, single-arm safety extension study of an age-and bodyweightadjusted oral finerenone regimen, in addition to an ACEI or ARB, for the treatment of children and young adults from 1 to 18 years of age with chronic kidney disease and proteinuria
Principle Investigator
Dr Alexandra Goischke
Total planned patients
2
Design
International, multicentre
Evaluation of Novel Biomarkers for Early Detection of Renal Injury in Children at increased risk to develop chronic kidney disease: a prospective study
Principle Investigator
Dr Alexandra Goischke
Total planned patients
418
Design
National, multicentre
Pilotstudy for Evaluation of new Biomarkers in Kids with Celiac Disease.
Principle Investigator
Dr Patricia Dill
Total planned patients
20
Design
national, monocentre
Paediatric Arteriopathy Steroid Aspirin High dose steroids in children with stroke and unilateral focal arteriopathy
Principle Investigator
Prof Dr med Alexandre Datta
Total planned patients
24 (4 in Basel)
Design
International, multicentre
Prognosis, treatment, and mechanisms in an international paediatric onset opsoclonus myoclonus ataxia syndrome (POOMAS) database and virtual biobank
Principle Investigator
Prof Dr med Andrea Klein
Total planned patients
Open register
Design
International, multicentre
Effect of pulsatile GnRH therapy on cognition in Down syndrome
Principle Investigator
Dr med Mark Brotzmann
Total planned patients
5–10
Design
national, multicentre
Study title
Swiss Primary Hypersomnolence and Narcolepsy Study
Principle Investigator
Prof Dr med Alexandre Datta
Total planned patients
(2-5 in Basel)
Design
National, multicentre
Observational study to understand acceptability of various available midazolam formulations (syrup, rectal suppository, oro-dispersible minitablet) in clinical practice
Principle Investigator
Dr Svetlana Beglinger, MD
Total planned patients
70
Design
National, multicentre
Prospective pharmacologic characterisation of a novel cytomegalovirus-infection prophylaxis (Letermovir) in pediatric hematopoietic cell transplantation patients using endogenous coproporphyrin (LetPeCo)
Principle Investigator
PD Dr Tamara Diesch
Total planned patients
15 patients, Basel 6-7, Geneva 8
Design
Multicentre, national
Swiss Childhood cancer Survivor Study-Follow up, Follow Up- Lung health after childhood cancer
Principle Investigator
Prof Nicolas von der Weid, MD
Total planned patients
60-80
Design
National, multicentre
Study to investigate lung development in children and adolescents during and after cancer therapy
Principle Investigator
Dr Christina Schindera
Total planned patients
150
Design
National, multicentre
No ongoing studies at present.
Multicentre, open-label, efficacy, tolerability and pharmacokinetic study of subcutaneous Ixekizumab with Adalimumab reference arm in children with juvenile idiopathic arthritis subtypes of enthesitis- related arthritis (including juvenile-onset ankylosing spondylitis) and juvenile psoriatic arthritis.
Principle Investigator
Dr Andreas Wörner
Total planned patients
100 patients (5 patients in Basel)
Design
International, multicentre
20200105: A Phase 3, Open-Label, Multicenter, Randomised Study to Evaluate the Efficacy and Safety of Romosozumab Compared with Bisphosphonates in Children and Adolescents with Osteogenesis Imperfecta
Principle Investigator
Dr Andreas Wörner
Total planned patients
100 patients (5 patients in Basel)
Design
International, multicentre
Patient and Public Involvement & Engagement
Principle Investigator
Prof Dr med Julia Bielicki
Total planned patients
–
Design
International, monocentre
Acne detection software
Principle Investigator
Prof Dr med Alexander Navarini
Included patients
40 (20 in Basel)
Design
National, multicentre
Advanced Diagnostics for Enhanced Quality of Antibiotic Prescription in Respiratory Tract Infections in Emergency rooms
Principle Investigator
PD Dr Julia Bielicki
Included patients
500 (75 in Basel)
Design
International, multicentre
Principle Investigator
Prof Dr med Julia Bielicki
Total planned patients
700 (112 in Basel)
Design
International, multicentre
Randomised Evaluation of COVID-19 Therapy (RECOVERY) in Children With PIMS-TS in Switzerland
Principle Investigator
PD Dr Julia Bielicki
End of study
76
Design
International, multicentre
A randomized, double-blind, Phase 3 study to investigate efficacy and safety of teplizumab compared with placebo in participants 1 to 25 years of age with recently diagnosed Stage 3 Type 1 Diabetes (T1D)
Principle Investigator
PD. Dr med. Marie-Anne Burckhardt
Planned patients
5
Design
international, multicentre, phase 3
Sponsor
Sanofi-Aventis Recherche & Développement, 82 Avenue Raspail, 94250 Gentilly, FRANCE
PIPELINE-RSV trial: an adaptive platform trial to evaluate strategies for the prevention of RSV in infants
Principle Investigator
Prof Dr med Julia Bielicki
Planned patients
Design
international, multicentre
058 387 78 82 (Costs are settled via the health insurance company)
In the event of an emergency abroad, call the emergency number of your health insurance company. You will find the contact details on your health insurance card.
145 (Poison and Information Centre)
University Children's Hospital of both
Basel, Spitalstrasse 33
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Phone +41 61 704 12 12
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The Medgate Kids Line provides quick and uncomplicated medical advice if your child is unwell. The medical team of our partner Medgate is available to you by telephone around the clock.
For emergencies abroad: Call the emergency number of your health insurance company. You will find this number on your health insurance card.
More information: On the Page of the emergency ward you will find everything you need to know about behaviour in emergencies, typical childhood illnesses and waiting times.
144 Outpatient clinic
145 Tox Info Suisse (Poisonings)
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