Since 2014
Professor of Systems Pharmacology and Pharmacometrics, Faculty of Medicine, University of Basel Deputy Chairman of the Department of Paediatric Pharmacology, University Children's Hospital Basel (UKBB) and Swiss Research Centre for Paediatric Pharmacology and Pharmacometrics (SwissPedPha)

2011 – 2014
Chief Medical Officer, Quantitative Solutions/Certara

2007 – 2010
Executive Director, Discovery Medicine & Clinical Pharmacology and Head of Strategic Modelling & Simulation, Research & Development, Bristol-Myers Squibb, Princeton, USA

2004 – 2007
Medical Director, Discovery Medicine & Clinical Pharmacology, Research & Development, Bristol-Myers Squibb, Princeton, USA

2002 – 2004
Associate Clinical Director, Research & Development, Sanofi-Aventis, Bridgewater, USA

2000 – 2002
Fellowship - Biopharmaceutical Sciences/Clinical Pharmacology, University of California, San Francisco, USA

1994 – 1999
Clinical Training - Internal Medicine and Nephrology, University of Bern, Switzerland

2001
Certificate in Advanced PK/PD Modelling, University of California San Francisco, USA

2000
Specialisation - Nephrology, University of Bern, Switzerland

1997
Specialisation - Internal Medicine, University of Bern, Switzerland

1990
Diploma in Tropical Medicine and Public Health, University of Basel, Switzerland

1988
Doctor of Medicine, University of Bern, Switzerland

2013
Leadership Award at the ACoP - International Society of Pharmacometrics

2008
Fellow - American College of Clinical Pharmacometrics

Editor Board Member
CPT Pharmacometrics and Systems Pharmacology
Journal of Clinical Pharmacology
Current Therapeutic Research
Journal of Diabetes Research and Therapy
Diabetes Obesity & Metabolism

2012 – 2013
President of the International Society of Pharmacometrics with 1000 members from 30 countries (ISoP, www.go-isop.org)

2012
Co-chair of the joint ASCPT-ASoP conference

2011
Co-founder, treasurer and board member of the American Society of Pharmacometrics (ASoP)

2010 – 2011
Chairman of the Pharmacometrics (PMK) Section of the American Society of Clinical Pharmacology & Therapeutics (ASCPT)

2008 – 2013
Regent/Member of the Board of the American College of Clinical Pharmacology (ACCP)

2008 – 2011
Co-founder and faculty member of the American Conference on Pharmacometrics (ACoP, www.acop6.org)

2008
Co-Chair of the 38th ACCP Annual Conference

• Clinical and "virtual" experimental research to optimise the research, development and use of drugs, especially in paediatrics.
• Systems pharmacology to characterise the course of disease, the effects of diseases on drugs and the effects of drugs on diseases in adults and children.
• Pharmacometrics (computer modelling and simulation) to identify and quantify pharmacogenetic and/or environmental factors that influence the exposure or efficacy/safety response of drugs in adults and children.
• Software packages and web-based platforms for the integration, exploration, visualisation and model-based analysis of large databases; decision support at the bedside for the evaluation and optimisation of treatment strategies in paediatrics.