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Emergency Contact 24h

0900 712 712

(3.23 CHF / min. from the Swiss landline, possibly additionally 8 Rp. / min. by network operator)

 
 

0900 712 713

(3.12 CHF / min. for calls from prepaid cell phones, possibly additionally 8 Rp. / min. by network operator)


Important Numbers

  • 144   Ambulance
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  • 117   Police
  • 118   Fire Department

Kontakt Box

UKBB

University Children’s Hospital Basel
Spitalstrasse 33
4056 Basel
Switzerland

T +41 61 704 12 12
F +41 61 704 12 13

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For making an appointment or the postponement of an appointment, please contact polyclinic head office +41 61 704 12 20

 
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Botnar Professorship

Breath is an underexploited body fluid, which contains valuable biochemical information at the metabolic level. Our mission is to uncap the potential that breath analysis holds as a non-invasive method to assist in clinical decision making. We are a multidisciplinary team of scientists embedded at the University of Basel Children’s Hospital (UKBB) since June 2017. Being physically rooted within a clinical context provides us with the unique advantage of interacting with clinicians and having direct access to patients.

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Secondary Electrospray Ionization-High Resolution Mass Spectrometry (SESI-HRMS) breath analysis platform at UKBB. This technique allows us to capture rich metabolic breath-prints of patients in a totally non-invasive and real-time fashion.

Ongoing Research Projects

Pneumonia is the leading infectious cause of death worldwide, mainly among children. For example, pneumonia accounts for 15% of all deaths in children less than 5 years of age (an estimated 935,000 children each year). Globally, pneumonia affects approximately 450 million people, and results in about 4 million deaths, per year. Hence, it exacts an enormous cost in economic and human terms. Early diagnosis is crucial for treatment success and improvement of outcome. However, the high morbidity and mortality of pneumonia is partly due to the lack of efficient diagnostics.

Our ultimate objective will be diagnosing bacterial pneumonia using a non-invasive breath test, that will deliver a positive/negative response and will identify a subset of causing pathogens in ~15 min. The figure describes the clinical problem and the proposed solution.

This work is part of the Zurich Exhalomics project under the umbrella of "University Medicine Zurich/Hochschulmedizin Zürich"

Diagnosis of bacterial pneumonia (Funded by the Swiss National Science Foundation)

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Collaborations

Patents

  1. Martinez-Lozano Sinues, P.; Fernandez de la Mora, J. Method to analyze and classify persons and organisms based on odor patterns from released vapors; US 9,121,844 B1. 2015 http://www.google.com.pg/patents/US9121844
  2. Gomez Moreno, F. J.; Martinez-Lozano Sinues, P.; Martin Espigares, M. System to reduce the pressure drop in a differential mobility analyzer; US 8,071,940 B2. 2011
    https://www.google.com/patents/US8071940

Open Positions

Master and Semester Projects

We offer the opportunity to make master and semester projects in the areas of breath analysis with Secondary Electrospray Ionization-Mass Spectrometry (SESI-MS)

If you are interested, please send applications with CV and grade transcripts to Prof. Dr. Pablo M-L Sinues.

Outrearch Activities

Only available in German

 

Emergencies

0900 712 712

(3.23 CHF/min. CH-landline, possibly additionally 8 Rp. / min. by network operator)

0900 712 713

(3.12 CHF/min. prepaid cell phones, possibly additionally 8 Rp. / min. by network operator)

Site Map

Contact

University Children’s Hospital Basel
Spitalstrasse 33
4056 Basel / Switzerland

T +41 61 704 12 12
F +41 61 704 12 13

 

Emergency

Contact

University Children’s Hospital Basel
Spitalstrasse 33
4056 Basel / Switzerland

T +41 61 704 12 12
F +41 61 704 12 13

© UKBB, 2018