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A reference centre of the National Coordination of Rare Diseases (kosek) meets high standards in the care, education and research of rare diseases. It offers specialised consultation hours and information and coordinates a range of services for those affected across all ages. The aim is to provide the best possible support and care for children, adolescents and adults with rare diseases.
REN Basel is a joint programme of the University Children's Hospital Basel (UKBB) and the University Hospital Basel (USB). Since 2024, this programme has been recognised by the cosecwhich is committed to improving the care situation for people affected by rare diseases.
As a university centre, we care for patients with rare kidney diseases from childhood to adulthood. Thanks to better therapies, life expectancy is high today - we therefore support many patients for decades. The close collaboration between UKBB and USB enables coordinated, cross-age care. One example is our joint transition consultation, which supports the transition from paediatric to adult nephrology. We also work closely together in training and further education. Despite modern therapies, many rare kidney diseases are progressive. Often the only effective therapy is a kidney transplant. The USB is one of the leading transplant centres for kidney transplants in Switzerland - many transplant patients suffer from rare kidney diseases. The USB is also heavily involved in research and transplant immunology.
REN Basel is part of the national RARE-Kidney network and is active in the „Working Group on Rare and Inherited Kidney Disorders“ of the Swiss Society of Nephrology. Through these networks, we promote nationwide exchange, training and research into rare kidney diseases.
On referral, we assess patients suspected of having a rare kidney disease and also provide further care if required.
FIONA (international, multicentre): A 6-month multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety and PK/PD of an age-and body weight-adjusted oral finerenone regimen, in addition to an ACEI or ARB, for the treatment of children, 6 months to <18 years of age, with chronic kidney disease and proteinuria
FIONA OLE (international, multicentre): An 18-month, open-label, single-arm safety extension study of an age-and bodyweightadjusted oral finerenone regimen, in addition to an ACEI or ARB, for the treatment of children and young adults from 1 to 18 years of age with chronic kidney disease and proteinuria
KidneyCheck (national, monocentre): Evaluation of Novel Biomarkers for Early Detection of Renal Injury in Children at increased risk to develop chronic kidney disease: a prospective study
CaVe (national, monocentre): Capillary versus venous blood test: Validation study for the optimisation of clinical laboratory tests in pediatrics
Ingold, M. Dickenmann, Th. Menter, H. Hopfer, P. Hirt-Minkowski. Successful Targeting of the Alternative Complement Cascade with Iptacopan for the Treatment of IgA Nephropathy: A Case Report. Accepted for publication in SMW 03/2025
Arnold, M. Nickler, M. Dickenmann, Th. Menter, H. Hopfer, P. Hirt-Minkowski First Successful Treatment of a Patient with a Primary Immune Complex-Membranoproliferative Glomerulonephritis with Iptacopan: A Case Report. Case Rep Nephrol Dial 2024; 14:138-147
Bahadori, A. Wilhelm-Bals, J. Caccia, H. Chehade, A. Goischke, C. Habre, D. Marx-Berger, S. Nef, O. Sanchez, G. Spart, I. Vidal, R. O. von Vigier, J. Birraux, P. Parvex. Swiss Consensus on Prenatal and Early Postnatal Urinary Tract Dilation: Practical Approach and When to Refer. Children 2024; 11:1561.
Schürch, G. Manegold-Brauer, H. Schönberger, J. Büchel, O. Lapaire, A. Butenschön, E. A. Huh, D. Huang, K. S. Evers, A. Goischke , M. Frech-Dörfler, Ch. Rudin. Diagnostic accuracy of an interdisciplinary tertiary centre evaluation in children referred for suspected congenital anomalies of the kidney and urinary tract on fetal ultrasound - a retrospective outcome analysis. Pediatr Nephrol 2021; 36:3885-3897
Kollbrunner, P. Hirt-Minkowski, J. Sanz, E. Bresin, TJ. Neuhaus, H. Hopfer, AW. Jehle. Case Report: Lipoprotein Glomerulopathy Complicated by Atypical Hemolytic Uremic Syndrome. Front Med 2021; 8:679048
Tsingo, L. Merlini, M. Solcà, A. Goischke, A. Wilhelm-Bals, P. Parvex. Early Urinary Biomarkers in Pediatric Autosomal Dominant Polycystic Kidney Disease (ADPKD): No Evidence in the Interest of Urinary Neutrophil Gelatinase-Associated Lipocalin (uNGAL). Front Pediatr 2019; 7:88
Hirt-Minkowski, M. Trendelenburg, I. Gröschl, A. Fischer, I. Heijnen, J. A. Schifferli. A trial of complement inhibition in a patient with cryoglobulin-induced glomerulonephritis. Case Rep Nephrol Urol 2012; 2:38-45
Hochuli, A. Stoller, M. Egger, R. Escher, M. Klein Lüthi, Hirt-Minkowski. Acute poststreptococcal glomerulonephritis - rare, but important enough not to be forgotten! Switzerland Med Forum 2011; 11:816-819
Hirt-Minkowski, M. Dickenmann, J.A. Schifferli. Atypical Hemolytic Uremic Syndrome: Update on the Complement System and What Is New. Nephron Clinical Practice 2010; 114:c219-c235
Hirt-Minkowski, S. Schaub, M. Mayr, J.A. Schifferli, M. Dickenmann, V. Frémeaux-Bacchi and J .Steiger. Haemolytic uraemic syndrome caused by factor H mutation: is single kidney transplantation under intensive plasmatherapy an option? Nephrology Dialysis Transplantation 2009; 24:3548-3551
The Medgate Kids Line provides quick and uncomplicated medical advice if your child is unwell. The medical team of our partner Medgate is available to you by telephone around the clock.
For emergencies abroad: Call the emergency number of your health insurance company. You will find this number on your health insurance card.
More information: On the Page of the emergency ward you will find everything you need to know about behaviour in emergencies, typical childhood illnesses and waiting times.
144 Outpatient clinic
145 Tox Info Suisse (Poisonings)
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